PeptidesInfo

Research

Research analyses

28 evidence-graded analyses. Every article separates human trials from animal research and marketing claims, and lists regulatory status separately.

Research analysis4 min read

Tesamorelin: Approved Use, Off-Label Interest, and Clinical Evidence

Tesamorelin is the one GHRH analogue that finished phase 3 and won FDA approval — for excess abdominal fat in HIV-associated lipodystrophy. We separate that established evidence from the off-label uses it is now marketed for: general visceral fat, liver fat, and cognition.

Research analysis4 min read

TB-500 and Thymosin Beta-4: What the Research Actually Studies

TB-500 is sold on the back of thymosin beta-4 research — a different molecule with real but early human trials in wounds and eye disease. We untangle which studies are about what, and what that means for the fragment people actually buy.

Research analysis4 min read

PT-141: Mechanism, Approved Use, Benefits, and Limitations

PT-141 (bremelanotide) is FDA-approved as Vyleesi for low sexual desire in premenopausal women, with modest benefits and a lot of nausea. Its use in men — the way it is mostly marketed online — was abandoned in development. Here is what the trials actually showed.

Research analysis4 min read

GHK-Cu: Skin, Hair, Wound Healing, and Evidence Quality

Copper peptide GHK-Cu has decades of laboratory work, small human trials for topical skin use, and a growing injectable market with no human data. We grade each claim — skin, hair, wounds, 'gene resetting' — separately.

Research analysis4 min read

Collagen Peptides: Joint, Skin, and Recovery Evidence

Oral collagen peptides are the rare non-drug peptide product with multiple randomised trials. The effects on skin hydration, activity-related joint pain and (with training) lean mass are real but small, and most trials are industry-funded. Here is what the studies show and where the gaps are.

Regulation6 min read

FDA-Approved, Off-Label, Investigational, and Unapproved Peptides

The regulatory status of a peptide is a fact about a decision, not a verdict on the evidence. This guide explains the four categories, what compounding rules changed in 2023–2025, and where every peptide we cover currently sits.

Foundations5 min read

How to Read Peptide Research Without Falling for Marketing

Most misleading peptide claims cite real studies. This guide shows how to tell a rat model from a human trial, a mechanism from an outcome, and a case report from evidence — with worked examples from BPC-157, growth hormone secretagogues and collagen research.

Foundations4 min read

What Are Peptides? A Research-Based Introduction

Peptides are short chains of amino acids that range from approved blockbuster drugs to unregulated 'research chemicals'. Here is what the word actually covers, how peptides differ from proteins and small-molecule drugs, and why the category tells you nothing about evidence.